Gregory Hawryluk is a fourth year resident in neurosurgery currently completing a PhD in neural repair and regeneration through the Institute of Medical Science under the supervision of Dr. Michael G. Fehlings.
Research Interests: Greg’s research seeks to understand the mechanism by which transplanted cells improve functional recovery following spinal cord injury.
Greg also has an interest in the management of CNS hemorrhage, and has published on the use of recombinant activated factor VII and more recently on the timing of acticoagulation resumption following central nervous system hemorrhage.
Thesis Title: Defining Neural Precursor Cell-Host Interactions to Optimize Repair of Traumatic Spinal Cord Injury
Thesis Synopsis Our group has previously shown that cellular transplantation leads to remyelination – or re-insulation – of nerves, but it is unclear if this accounts for the functional recovery noted in experimental animals. Greg is exploring the possibility that transplanted cells additionally secrete repair-promoting substances (called trophins) into the injured spinal cord as well as the possibility that these cells preserve tissue in addition to replacing it. Furthermore, he has explored whether these cells reduce scarring and inflammation.
Figures and supplementary data from Greg’s paper published in Cell Transplantation – Remyelination is the Key Mechanism by Which Neural Precursors Augment Recovery Following Rodent Spinal Cord Injury (Pubmed) can be viewed here